Fertility, contribution of the maternal inheritance

Monday 16th June 2025

First Session: From Soma to Germline: oocyte dormancy establishment

Chair: Elvan Böke

Jasmin Rettkowski (ETH Zurich): Stem Cells dormancy

Katsuhiko Hayashi (Osaka University, Japan): Germ Stem Cells culture to produce oocytes

First Session: From Soma to Germline: oocyte dormancy establishment

Chair: Elvan Böke

Jean-René Huynh (CIRB, France): Evolutionary Adaptations to Cellular Constraints in Meiotic Chromosome Pairing

Second Session: Establishing Maternal Reserves

Chair: Marie-Hélène Verlhac

Yaniv Elkouby (The Hebrew University of Jerusalem, Israël): Divisions of the germline cyst in Zebrafish

Petr Svoboda (Institute of Molecular Genetics, Praha): Small RNAs in oocytes

Second Session: Establishing Maternal Reserves

Chair: Marie-Hélène Verlhac

Geraldine Seydoux (Johns Hopkins School of Medicine, USA): Cytoplasm RNA dynamics in c. elegans

Arnaud Hubstenberger (IBV, France): Phase Separation of RNPs in c. elegans

Florence Marlow (Icahn School of Medicine at Mount Sinai, USA): Oocyte polarity

Second Session: Establishing Maternal Reserves

Chair: Marie-Hélène Verlhac

Short Talks selected on abstracts

Avishag Mytlis, Hebrew university of Jerusalem (on Zoom): The Zygotene Cilium Regulates Meiosis, Germ Cell Development, and Fertility in Zebrafish, Mice, and Humans

Karin Levy, Hebrew university of Jerusalem: Coordination of meiosis by nuclear-dependent Plk1 centrosome regulation co-organizes oocyte cellular compartments

Stephanie Rosswag de Souza, CRG Barcelona: Unraveling unique features of transcription and translation in oocytes

Anahi Molla-Herman, CIRB Collège de France: H2Av controls genome integrity and fertility in Drosophila female germline

Noemi Zollo, CIRB Collège de France: A novel RNP compartment boosts translation in growing mouse oocytes to avoid cytoplasm dilution

Antoine Guichet, IJM Paris: A dual system involving the nuclear envelope and membrane cortex ensures that the nucleus is anchored asymmetrically in the Drosophila oocyte

Yamiini Vadapalli, Max Planck Institute for Multidisciplinary Sciences: Actin and microtubules cooperate in chromosome capture during oocyte meiosis

Andrea Pauli (IMP, Austria): Life’s first kiss – what do we miss?

Tuesday 17th June 2025

Third Session: Preserving maternal stores via asymmetric divisions

Chair: Jean-René Huynh

Eva Hoffmann (University of Copenhagen, Denmark): Oocyte aneuploïdy

Karen Schindler (University of Rutgers, USA): Oocyte acentriolar Spindle Assembly

Third Session: Preserving maternal stores via asymmetric divisions

Chair: Jean-René Huynh

Michaël Lampson (University of Pennsylvania, USA): Meiotic drive during oocyte divisions

Third Session: Preserving maternal stores via asymmetric divisions

Chair: Jean-René Huynh

Carl-Philip Heisenberg (ISTA, Austria): Establishing oocyte polarity

Marie-Emilie Terret (CIRB, France): Biophysics of oocyte divisions

Third Session: Preserving maternal stores via asymmetric divisions

Chair: Jean-René Huynh

Short Talks selected on abstracts

Katja Wassmann, IJM Paris: Coordinating Chromosome Segregation with Cell Cycle Progression in Oocyte Meiosis

Thierry Lorca, CRBM Montpellier: Role of Gwl in regulating both Erp1 stabilization and Cdk1-APC/C activities, ensuring proper meiotic progression.

Tommaso Cavazza, University of Zurich: Parental genome unification is error prone in mammalian embryos 

Christopher Thomas, IBDM Marseille: Revealing the Secrets of Ovulation

Marzia Munafo, EMBL Rome: Precision genetic perturbations reveal the functional role of chromatin marks in oogenesis and inheritance

Rose Bulteau, CIRB Collège de France: Atomic Force Microscopy reveals differences in mechanical properties linked to cortical structure in mouse and human oocytes

Volodymyr Porokh, Masaryk University, Faculty of Medicine: Zygotic spindle orientation – biparental contribution to genetic stability

Melina Schuh (Max Planck, Germany): Mammalian oocyte divisions